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Season 3: All about the Lash & Brow Serum

Sensitivity, Safety & the Eye Area

Dr. Manfred Groeppel, Dr. Anne Asmuß 23.06.2026 02:46

In summary

  • It is not the eyelash itself but the follicle in the eye area that responds to active ingredients, and that is precisely where soluble CD83 works.
  • Prostaglandin derivatives can cause redness, dark circles, and permanent iris discoloration and are currently under review by multiple regulatory authorities.
  • The 8T3 Essentials Lash & Brow Serum contains no prostaglandins or prostaglandin analogues and is completely hormone-free.
  • The eye area is inherently sensitive: if irritation occurs, stop applying the product and give the skin time to settle.
FAQ

Sensitivity, Safety and the Eye Area

Why are eyelashes particularly sensitive to active ingredients?
It is not actually the eyelashes that react to active ingredients, but the eye area in which the eyelash follicles sit. The eye area is one of the most sensitive parts of the body, and any cosmetic or ointment applied there carries a risk of causing irritation.
Why has the 8T3 Essentials Lash & Brow Serum deliberately chosen not to use prostaglandin derivatives?
Prostaglandin derivatives can cause serious side effects including redness, dark circles, and iris discoloration. Multiple authorities have placed these ingredients under review, which is why Mallia has chosen to use only soluble CD83 instead.
Are the side effects of prostaglandins permanent?
Iris discoloration caused by prostaglandin derivatives is permanent and does not reverse. Dark circles may also remain permanently, though in some cases they do go away.
What should you watch out for when applying products to the eye area?
Because the eye area is inherently sensitive, even well-tolerated products can occasionally cause irritation. If that happens, stop using the product and give the area time to settle.
Why are promises of rapid eyelash growth a warning sign?
Every eyelash has its own natural growth cycle, and no product can speed it up. If someone claims otherwise, that is a reason to be cautious.
What does "well tolerated" actually mean for a lash serum?
Well tolerated means that no or very few side effects occur. Because the 8T3 Essentials Lash & Brow Serum contains no prostaglandin analogues, the side effects associated with those ingredients, such as hyperpigmentation or permanent iris discoloration, simply cannot occur.

Description

The eye area is one of the most sensitive parts of the body. Active ingredients do not act on the eyelashes themselves but on the follicle from which each lash grows. Soluble CD83 in the 8T3 Essentials Lash & Brow Serum works at exactly that level, influencing hair growth within the follicle. 

Prostaglandin derivatives have been used for years to promote eyelash growth, but are now under review by multiple regulatory authorities. Reported side effects include redness, hyperpigmentation, dark circles that may not reverse, and iris discoloration, typically from blue to brown, which is permanent. The 8T3 Essentials Lash & Brow Serum contains none of these ingredients and is hormone-free. 

If irritation does occur with any product, stopping application is the right step. Promises of unusually fast growth are a warning sign: no product can speed up the natural growth cycle of an eyelash.

Experts

Dr. Manfred Groeppel
Dr. Manfred Groeppel
Dr. Anne Asmuß
Dr. Anne Asmuß
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