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Season 2: All about Science

Active Ingredient & Mechanism of Action

Prof. Dr. Alexander Steinkasserer 26.05.2026 01:48

In summary

  • sCD83, researched for 25 years and produced using recombinant technology, is the active ingredient in the 8T3 Essentials Hair Serum 
  • The serum passively penetrates the hair follicle channels and works directly at the follicle, not on the hair itself 
  • sCD83 activates the follicle, extends the growth phase, and leads to thicker, improved hair growth 
  • Healthy hair follicles are immunoprivileged; in androgenetic alopecia, micro-inflammation disrupts this balance 
  • sCD83 restores the natural balance in the follicle environment
FAQ

Active Ingredient & Mechanism of Action

What is the active ingredient in the 8T3 Essentials Hair Serum?
The active ingredient is sCD83, soluble CD83. The molecule is produced using recombinant technology and is the result of 25 years of research.
How does the 8T3 Essentials Hair Serum work?
The serum passively penetrates the hair follicle channels, reactivates the follicles, and stimulates growth. It extends the growth phase and leads to improved, thicker hair growth.
Does MAL-838 act directly on the hair or on the area surrounding the hair follicle?
The 8T3 Essentials Hair Serum does not act on the hair itself, but directly on the hair follicle and its surrounding environment. It activates the follicle and extends its growth phase.
What is sCD83 and why is this molecule important for regeneration?
sCD83 activates hair follicles, extends the growth phase, and improves hair strand growth, resulting in better overall hair growth.
What role does immunomodulation play in hair growth and skin regeneration?
Healthy hair follicles are immunoprivileged, with no immune cells normally present. In androgenetic alopecia, micro-inflammation creates an inflammatory environment that damages the hair root. sCD83 restores the natural balance, recreating a healthy environment for the hair follicles.

Description

The active ingredient in the 8T3 Essentials Hair Serum is sCD83, soluble CD83. Prof. Dr. Alexander Steinkasserer has been researching this molecule for 25 years. Produced using recombinant technology, the serum passively penetrates the hair follicle channels and works directly at the follicle and its surrounding environment, not on the hair itself. 

sCD83 activates the hair follicle, extends its growth phase, and improves hair strand growth. The result is improved, thicker hair. 

There is an immunological mechanism behind this. Healthy hair follicles are immunoprivileged, meaning there are normally no immune cells present. In androgenetic alopecia, micro-inflammation creates an inflammatory environment that damages the hair root. sCD83 restores the natural balance.

Experts

Prof. Dr. Alexander Steinkasserer
Prof. Dr. Alexander Steinkasserer
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